Abstract

Fish cell lines, collectively referred to as the fish invitrome, are useful diagnostic tools to study radiation impacts on aquatic health and elucidate radiation mechanisms in fish. This paper will highlight the advantages, discuss the challenges, and propose possible future directions for uses of the fish invitrome in the field of environmental radiobiology. The fish invitrome contains at least 714 fish cell lines. However, only a few of these cell lines have been used to study radiation biology in fish and they represent only 10 fish species. The fish invitrome is clearly not yet explored for its full potential in radiation biology. Evidence suggests that they are useful and, in some cases, irreplaceable in making underlying theories and fundamental concepts in radiation responses in fish. The debate of whether environmental radiation is harmful, presents risks, has no effect on health, or is beneficial is on-going and is one that fish cell lines can help address in a time-effective fashion. Any information obtained with fish cell lines is useful in the framework of environment radiation risk assessments. Radiation threats to aquatic health will continue due to the very likely rise of nuclear energy and medicine in the future. The fish invitrome, in theory, lives forever and can meet new challenges at any given time to provide diagnostic risk analyses pertaining to aquatic health and environmental radiation protection.

摘要

鱼细胞系统称为鱼体外细胞系，是研究辐射对水生健康的影响和阐明鱼类辐射机制的有用诊断工具。本文将突出优点，讨论挑战，并提出未来在环境放射生物学领域中使用鱼体外的可能方向。鱼 invitrome 包含至少 714 个鱼细胞系。然而，这些细胞系中只有少数被用于研究鱼类的辐射生物学，它们仅代表 10 种鱼类。鱼invitrome显然尚未探索其在辐射生物学中的全部潜力。有证据表明，它们是有用的，在某些情况下，在制定鱼类辐射响应的基本理论和基本概念方面是不可替代的。关于环境辐射是否有害的争论，存在风险、对健康没有影响或有益的问题正在持续进行中，并且是鱼细胞系可以帮助以一种及时有效的方式解决的问题。用鱼细胞系获得的任何信息在环境辐射风险评估的框架中都是有用的。由于未来核能和医学的兴起，辐射对水生健康的威胁将继续存在。从理论上讲，鱼的邀请是永远存在的，并且可以在任何特定时间迎接新的挑战，以提供与水生健康和环境辐射防护有关的诊断风险分析。由于未来核能和医学的兴起，辐射对水生健康的威胁将继续存在。从理论上讲，鱼的邀请是永远存在的，并且可以在任何特定时间迎接新的挑战，以提供与水生健康和环境辐射防护有关的诊断风险分析。由于未来核能和医学的兴起，辐射对水生健康的威胁将继续存在。从理论上讲，鱼的邀请是永远存在的，并且可以在任何特定时间迎接新的挑战，以提供与水生健康和环境辐射防护有关的诊断风险分析。