Small-angle X-ray scattering (SAXS) is a widely used method for investigating biological macromolecules in structural biology, providing information on macromolecular structures and dynamics in solution. Modern synchrotron SAXS beamlines are characterized as high-throughput, capable of collecting large volumes of data and thus demanding fast data processing for efficient beamline operations. This article presents a fully automated and high-throughput SAXS data analysis pipeline, SAS-cam, primarily based on the SASTBX package. Five modules are included in SAS-cam, encompassing the data analysis process from data reduction to model interpretation. The model parameters are extracted from SAXS profiles and stored in an HTML summary file, ready for online visualization using a web browser. SAS-cam can provide the user with the possibility of optimizing experimental parameters based on real-time feedback and it therefore significantly improves the efficiency of beam time. SAS-cam is installed on the BioSAXS beamline at the Shanghai Synchrotron Radiation Facility. The source code is available upon request.

中文翻译：

---

SAS-cam：小角度散射数据自动处理分析程序

小角 X 射线散射 (SAXS) 是一种广泛用于研究结构生物学中生物大分子的方法，可提供有关大分子结构和溶液动力学的信息。现代同步加速器 SAXS 光束线的特点是高通量，能够收集大量数据，因此需要快速数据处理以实现高效的光束线操作。本文介绍了一种全自动和高吞吐量的 SAXS 数据分析管道 SAS-cam，主要基于 SASTBX 包。SAS-cam 包含五个模块，涵盖从数据简化到模型解释的数据分析过程。模型参数从 SAXS 配置文件中提取并存储在 HTML 摘要文件中，准备使用 Web 浏览器进行在线可视化。SAS-cam可以为用户提供基于实时反馈优化实验参数的可能性，从而显着提高束时间的效率。SAS-cam 安装在上海同步辐射装置的 BioSAXS 光束线上。可根据要求提供源代码。