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Isochamaejasmin induces toxic effects on Helicoverpa zea via DNA damage and mitochondria-associated apoptosis.
Pest Management Science ( IF 4.1 ) Pub Date : 2020-08-19 , DOI: 10.1002/ps.6055
Yuanhang Ren 1, 2 , Qiang Li 1, 2 , Lidan Lu 1, 2 , Hong Jin 2 , Ke Tao 2 , Taiping Hou 2
Affiliation  

Stellera chamaejasme L. is a poisonous plant with rich resources and is thus highly valuable in terms of new pesticide development. Isochamaejasmin (ICM), one of the main ingredients in S. chamaejasme has drawn much attention owing to its antitumour properties. However, the toxicity and mode of action of ICM on insects are still not clear. In this article, the larva and neuronal cell (AW1) of Helicoverpa zea were used to clarify the insecticidal activity of ICM as well as its toxic mechanism at the cellular level.

中文翻译:

异麦芽茉莉通过DNA损伤和线粒体相关凋亡诱导对Helicoverpa zea的毒性作用。

Stellera chamaejasme L.是一种有毒植物,资源丰富,因此在开发新农药方面具有很高的价值。异豆蔻茉莉(ICM)是沙门氏菌(S. chamaejasme)的主要成分之一,由于其抗肿瘤特性而备受关注。但是,ICM对昆虫的毒性和作用方式仍不清楚。在本文中,Helicoverpa zea的幼虫和神经元细胞(AW1)用于阐明ICM的杀虫活性及其在细胞水平上的毒性机制。
更新日期:2020-08-19
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