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5‐Aminolevulinic Acid‐mediated Photodynamic Therapy has Effective Antifungal Activity against Sporothrix globosa In Vitro
Mycoses ( IF 4.9 ) Pub Date : 2020-09-12 , DOI: 10.1111/myc.13171
Ruili Chen 1 , Yang Song 1 , Yu Zhen 1 , Lei Yao 1 , Ying Shi 1 , Yan Cui 1 , Shanshan Li 1
Affiliation  

An alternative therapy for sporotrichosis is necessary to reduce the treatment time and raise clinical efficacy. The 5‐Aminolevulinic acid‐mediated photodynamic therapy (ALA‐PDT) is a promising platform with which to treat mycoses. However, despite the worldwide prevalence of Sporothrix globosa, a causative agent of sporotrichosis, the effect of ALA‐PDT on this pathogen has not been validated.

中文翻译:

5-氨基乙酰丙酸介导的光动力疗法在体外对球形孢子丝菌具有有效的抗真菌活性

孢子丝菌病的替代疗法对于缩短治疗时间和提高临床疗效是必要的。5-氨基乙酰丙酸介导的光动力疗法(ALA-PDT)是治疗真菌病的有前途的平台。然而,尽管球形孢子丝菌(一种孢子丝菌病的病原体)在世界范围内流行,但 ALA-PDT 对这种病原体的影响尚未得到证实。
更新日期:2020-09-12
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