Human pluripotent stem cells offer a limitless source of cells for regenerative medicine. They are also highly valuable as tools to study development and pathologies or as cellular substrates to screen and test new drugs. We generated human induced pluripotent stem cell (hiPSC) lines from two unrelated healthy control donors. Peripheral blood mononuclear cells (PBMCs) from these donors were reprogrammed by non-integrative viral transduction, had normal karyotypes and expressed pluripotency hallmarks.

中文翻译：

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从健康供体中产生两种诱导的多能干细胞系IMAGINi004-A和IMAGINi005-A。

人多能干细胞为再生医学提供了无限的细胞来源。它们作为研究发展和病理的工具或筛选和测试新药的细胞底物也非常有价值。我们从两个无关的健康对照供体中产生了人诱导的多能干细胞（hiPSC）系。这些供体的外周血单个核细胞（PBMC）通过非整合型病毒转导进行了重新编程，具有正常的核型和表达的多能性标志。