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Dose evaluation of 142Pr radioisotope by Monte Carlo method in eye brachytherapy
Radiation Physics and Chemistry ( IF 2.8 ) Pub Date : 2020-12-01 , DOI: 10.1016/j.radphyschem.2020.109150
Neslihan Koyuncu , İskender Atilla Reyhancan

Abstract Brachytherapy is one of the important methods of cancer treatment. The dosimetry characterization should be performed before any possibility of the new sources is used at a clinical stage. Monte Carlo methods are best to calculate the dosimetry parameters of the radioactive sources. Therefore, dosimetry parameters of beta-emitting 142Pr radioactive source were evaluated according to the recommendations of AAPM TG 43 and TG 60 using MCNP5 code. Reference dose rate, geometry function, radial dose function, and anisotropy function were calculated for 142Pr brachytherapy seed. Beta particles from 142Pr source have short-range and this prevents to damage the healthy tissue. Hence, 142Pr is suitable for superficial tumors like eye cancer. As a result, eye geometry was simulated and the dose distribution of 142Pr radioactive seed was determined using with MCNP5 code to develop a brachytherapy treatment for eye cancer.

中文翻译:

142Pr放射性同位素在眼部近距离放射治疗中的蒙特卡罗法剂量评价

摘要 近距离放射治疗是治疗癌症的重要方法之一。在临床阶段使用任何可能的新来源之前,应进行剂量学表征。蒙特卡罗方法最适合计算放射源的剂量学参数。因此,根据AAPM TG 43 和TG 60 的建议,使用MCNP5 代码评估β 发射142Pr 放射源的剂量学参数。计算了 142Pr 近距离放射治疗种子的参考剂量率、几何函数、径向剂量函数和各向异性函数。来自 142Pr 源的 Beta 粒子具有短射程,这可以防止损坏健康组织。因此,142Pr 适用于眼癌等浅表肿瘤。因此,
更新日期:2020-12-01
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