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Reference Intervals for Bone Histomorphometric Measurements Based on Data from Healthy Premenopausal Women.
Calcified Tissue International ( IF 3.3 ) Pub Date : 2020-08-20 , DOI: 10.1007/s00223-020-00748-6
Shijing Qiu 1 , George Divine 2 , Elizabeth Warner 3 , Sudhaker D Rao 1, 3
Affiliation  

This study has established the normal reference intervals for bone histomorphometric measurements derived from healthy premenopausal women, which is rarely available. We presented the static and dynamic bone histomorphometric data from trans-iliac bone biopsies in 62 healthy premenopausal women (19 blacks and 43 whites, ages 20–53 years). There were no significant differences in age and BMI between black and white women. Since there was no significant difference in bone remodeling between the two ethnic groups, we pooled data of all 62 premenopausal women to establish normal reference intervals for bone histomorphometry. The results provide normal reference intervals for both static and dynamic histomorphometric variables in cancellous and cortical bone of the ilium. None of the bone remodeling-related variables correlated with age or BMI. This study provides reference intervals for bone histomorphometric measurements in both cancellous and cortical bone of the ilium, which would be helpful in the evaluation of bone health in women.



中文翻译:

基于健康绝经前妇女数据的骨组织形态测量参考间隔。

本研究为健康绝经前妇女的骨组织形态测量建立了正常参考区间,而这很少可用。我们展示了来自 62 名健康绝经前女性(19 名黑人和 43 名白人,年龄 20-53 岁)的经髂骨活检的静态和动态骨组织形态学数据。黑人和白人女性的年龄和 BMI 没有显着差异。由于两个种族之间的骨重建没有显着差异,我们汇总了所有 62 名绝经前妇女的数据,以建立骨组织形态计量学的正常参考区间。结果为髂骨松质骨和皮质骨中的静态和动态组织形态测量变量提供了正常的参考区间。没有任何骨重建相关变量与年龄或 BMI 相关。

更新日期:2020-08-20
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