Radio telemetry systems are a useful way to continuously monitor broad electrical neuronal activity in behaving animals. It can also be used to study sleep disturbances or monitor seizure activity. Many different telemeter styles are available, but the more versatile and cost-efficient ones are the head mounted systems. They permit long-term recordings and allow more flexibility in the recordings. However, there are currently no such system available for non-human primate (NHP). In fact, the choices for NHP telemetry solutions are very limited. Here, we present a chronically implantable 3D printed chamber specifically designed to accommodate a rodent head-mounted system (RodentPACK) onto a NHP’s head. We recorded EEG signal for more than a year, confirmed quality of the signal, and the ability to use the data to monitor sleep activity. We also used two of our epileptic animals to validate the embedded alarm system for real time seizure monitoring. While initially not designed for NHP, but with a minimum number of adaptions, this telemeter is in fact perfectly suitable for NHP experiments. Since early medical intervention during seizures is critical to avoid status epilepticus and to save the animal’s life, real time seizures monitoring is becoming a safety requirement in many NHP studies. This method refines the current seizure monitoring methods for NHP and creates a flexible telemetry solution.

无线电遥测系统是连续监测行为动物广​​泛的电神经元活动的有用方法。它还可用于研究睡眠障碍或监测癫痫发作活动。有许多不同的遥测类型可供选择，但更通用和更具成本效益的是头戴式系统。它们允许长期录音，并在录音中提供更大的灵活性。然而，目前没有可用于非人类灵长类动物 (NHP) 的此类系统。事实上，NHP 遥测解决方案的选择非常有限。在这里，我们展示了一个长期可植入的 3D 打印室，专门设计用于将啮齿动物头戴式系统 (RodentPACK) 安装到 NHP 的头部。我们记录了一年多的 EEG 信号，确认了信号的质量，以及使用数据监测睡眠活动的能力。我们还使用了我们的两只癫痫动物来验证嵌入式警报系统，以进行实时癫痫监测。虽然最初不是为 NHP 设计的，但经过最少的调整，这款遥测仪实际上非常适合 NHP 实验。由于癫痫发作期间的早期医疗干预对于避免癫痫持续状态和挽救动物生命至关重要，因此在许多 NHP 研究中，实时癫痫发作监测已成为一项安全要求。该方法改进了 NHP 当前的癫痫监测方法，并创建了一个灵活的遥测解决方案。由于癫痫发作期间的早期医疗干预对于避免癫痫持续状态和挽救动物生命至关重要，因此在许多 NHP 研究中，实时癫痫发作监测已成为一项安全要求。该方法改进了 NHP 当前的癫痫监测方法，并创建了一个灵活的遥测解决方案。由于癫痫发作期间的早期医疗干预对于避免癫痫持续状态和挽救动物生命至关重要，因此在许多 NHP 研究中，实时癫痫发作监测已成为一项安全要求。该方法改进了 NHP 当前的癫痫监测方法，并创建了一个灵活的遥测解决方案。