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Organ-on-a-Chip Engineered Microenvironments for Safety and Efficacy Testing
IEEE Pulse ( IF 0.3 ) Pub Date : 2020-07-01 , DOI: 10.1109/mpuls.2020.3008454
Paul H. King

The need to improve testing platforms for current and new pharmaceuticals has helped generate studies involving “organs-on-a-chip” technologies in recent years. This text, aimed at a readership including biomedical engineers, entrepreneurs, design engineers, new drug investigators, etc., attempts to survey the current state of the art in this area of endeavor. It does this well, with 15 chapters from 36 contributors from eight countries. The text covers the many justifications for this work, multiple examples of platforms involving one or more lines of organ cells, discussion of the technologies involved in system design, and one chapter giving an example of a multi-organ-on-a-chip design.

中文翻译:

用于安全和功效测试的器官芯片工程微环境

近年来,需要改进当前和新药物的测试平台,这有助于产生涉及“芯片器官”技术的研究。本书面向包括生物医学工程师、企业家、设计工程师、新药研究人员等在内的读者,试图调查该领域的当前技术水平。它做得很好,有来自八个国家的 36 位贡献者的 15 章。文本涵盖了这项工作的许多理由,涉及一个或多个器官细胞系的平台的多个示例,系统设计中涉及的技术的讨论,以及一个给出多器官芯片设计示例的章节.
更新日期:2020-07-01
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