Perhaps the most important step when designing and conducting randomized controlled trials (RCTs) in addiction is to put methodological safeguards in place to minimize the likelihood for bias to affect trial outcomes. In this study, we applied the revised Cochrane risk of bias tool (ROB 2) to RCTs of drug, alcohol or tobacco interventions.

中文翻译：

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成瘾药物随机对照试验中偏倚风险的评估。

在设计和进行成瘾随机对照试验 (RCT) 时，最重要的一步可能是采取方法学保障措施，以尽量减少偏倚影响试验结果的可能性。在本研究中，我们将修订后的 Cochrane 偏倚风险工具 (ROB 2) 应用于药物、酒精或烟草干预的 RCT。