Any attempt to control a mosquito‐borne disease should primarily focus on controlling its vector. In Sudan, arboviral infections are a major health problem where periodical outbreaks of arboviruses transmitted by Aedes aegypti have been reported. This preliminary study was performed to uncover the population genetic diversity of Aedes aegypti from Red Sea State, Sudan, using mtDNA‐COI gene. We performed morphological identification, PCR and DNA nucleotide sequencing and analysed the genetic polymorphism, and isolation by distance of Aedes aegypti from four sites. Of the 55 samples successfully sequenced, six haplotypes were revealed. Global haplotype network revealed that the predominant haplotype in Sudan (Hap1; 31 sequences = 56.4%), the second most frequent haplotype (Hap2; 13 sequences = 23.6%) and Hap 5 (3.6%) were identical or genetically close to isolates seen in different countries distributed in the United States, South America, Europe, Asia and two African isolates, one from Kenya and the other from Europa Island (Mozambique Channel). Haplotype 4 (3.6%) appeared closely related to mosquitoes sampled from Cameroon, Kenya, Sri Lanka and India and belonged to a lineage that contained isolates from all over the geographical expansion. Haplotype 6 (1.8%) seemed quite distant from any other sequenced mtDNA. To summarize, four haplotypes were found only in Sudan, and one rare haplotype appeared genetically distant from all other haplotypes, suggesting a local origin. Subdivision measures and testing suggested a probable free (or almost free) migration between the different sites sampled.

中文翻译：

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苏丹港埃及伊蚊的独特单倍型和自由活动

任何控制蚊媒疾病的尝试都应主要集中在控制其媒介上。在苏丹，虫媒病毒感染是一个主要的健康问题，据报道，埃及伊蚊传播的虫媒病毒周期性爆发。这项初步研究旨在利用 mtDNA-COI 基因揭示苏丹红海州埃及伊蚊的种群遗传多样性。我们进行了形态学鉴定、PCR 和 DNA 核苷酸测序，并分析了埃及伊蚊的遗传多态性和从四个位点的距离分离。在成功测序的 55 个样本中，揭示了 6 个单倍型。全球单倍型网络显示，苏丹的主要单倍型（Hap1；31 个序列 = 56.4%）、第二常见的单倍型（Hap2；13 个序列 = 23.6%）和 Hap 5（3. 6%) 与分布于美国、南美、欧洲、亚洲的不同国家的分离株相同或在遗传上接近，以及两种非洲分离株，一种来自肯尼亚，另一种来自欧罗巴岛（莫桑比克海峡）。单倍型 4 (3.6%) 似乎与从喀麦隆、肯尼亚、斯​​里兰卡和印度采样的蚊子密切相关，属于一个谱系，其中包含来自整个地理扩展的分离株。单倍型 6 (1.8%) 似乎与任何其他已测序的 mtDNA 相距甚远。总而言之，仅在苏丹发现了四种单倍型，一种罕见的单倍型在遗传上与所有其他单倍型相距甚远，表明其起源于当地。细分措施和测试表明，不同采样点之间可能存在自由（或几乎自由）迁移。