In recent years, manipulation of particles by inertial microfluidics has attracted significant attention. However, most studies focused on inertial focusing of particles suspended within liquid phase, in which the ratio of the density of the particle to that of the medium is O(1). The investigation on manipulation of aerosol particles in an inertial microfluidics is very limited. In this study, we numerically investigate the aerosol particle's motion in a 3D straight microchannel with rectangular cross section by fully resolved simulation of the particle–air flow. The air flow is modeled by the Navier–Stokes equations. The particle's motions, including translation and rotation, are governed, respectively, by the Newton's second law and the Euler equations without using any approximation models for the lift and drag forces. The coupled mathematical model is numerically solved by combining immersed boundary with lattice Boltzmann method (IB-LBM). We find that the Reynolds number (Re), the particle's initial position, particle's density and diameter are the influential parameters in this process. The equilibrium positions and their stabilities of aerosols are different from those suspended in liquid.

近年来，惯性微流控颗粒的研究引起了人们的广泛关注。然而，大多数研究集中于悬浮在液相中的颗粒的惯性聚焦，其中颗粒的密度与介质的密度之比为O (1)。在惯性微流体中操纵气溶胶颗粒的研究非常有限。在这项研究中，我们通过对颗粒-空气流的完全解析模拟，对气溶胶颗粒在具有矩形横截面的 3D 直微通道中的运动进行数值研究。气流由纳维-斯托克斯方程建模。粒子的运动，包括平移和旋转，分别由牛顿第二定律和欧拉方程控制，而不使用任何升力和阻力的近似模型。将浸没边界与格子玻尔兹曼法（IB-LBM）相结合，对耦合数学模型进行数值求解。我们发现雷诺数（ Re ）、粒子的初始位置、粒子的密度和直径是该过程的影响参数。气溶胶的平衡位置及其稳定性与悬浮在液体中的不同。