Calix[4]pyrrole and its derivatives are key members of the supramolecular Parthenon along with other well-recognized receptor systems, such as crown ethers, cyclodextrins (CDs), cucurbiturils, calixarenes and pillararenes. Calix[4]pyrroles are relatively easy–to–make and widely recognized for their ability to bind anions and ion pairs. Many review papers relating to aspects of calix[4]pyrrole chemistry have been published within the past decades. These reviews have focused primarily on monomeric calix[4]pyrroles. The emergent area of bis–calix[4]pyrroles, species wherein two calix[4]pyrrole subunits are linked by one or more “walls”, has not benefited from such treatment, even though the species in question often exhibit enhanced binding affinities and selectivities relative to their single calix[4[pyrrole congeners. This review is designed to summarize recent progress involving bis–calix[4]pyrroles. Advances in the design, synthesis, and coordination chemistry of bis–calix[4]pyrroles containing “one wall”, “two walls”, “three walls”, and “four walls”, as well as their possible application in ion recognition, sensing and logic gate construction, will be detailed. The hope is that this review will provide a guide for the design and preparation of new multi-component calix[4]pyrrole receptors possessing improved recognition properties, thereby advancing host–guest chemistry in new and useful directions.

Calix [4]吡咯及其衍生物是超分子帕台农神庙以及其他公认的受体系统（例如冠醚，环糊精（CD），葫芦科，杯芳烃和柱芳烃）的关键成员。杯[4]吡咯相对易于制造，并因其结合阴离子和离子对的能力而广为人知。在过去的几十年中，已经发表了许多有关杯[4]吡咯化学方面的综述文章。这些评论主要集中于单体杯[4]吡咯。尽管两个有杯[4]吡咯亚基通过一个或多个“壁”相连的双杯[4]吡咯的出苗区域均未从这种处理中受益，尽管该物种经常表现出增强的结合亲和力和相对于其单一杯[4 [吡咯同类物]的选择性。这篇综述旨在总结涉及双杯[4]吡咯的最新进展。包含“一个壁”，“两个壁”，“三个壁”和“四个壁”的双杯[4]吡咯的设计，合成和配位化学的进展，以及它们在离子识别中的可能应用，传感和逻辑门的构造，将详细介绍。希望这篇综述将为设计和制备具有改进的识别特性的新型多组分杯[4]吡咯受体提供指导，从而在新的有用方向上促进宿主-客体化学。以及它们在离子识别，传感和逻辑门构造中的可能应用将被详细介绍。希望这篇综述将为设计和制备具有改进的识别特性的新型多组分杯[4]吡咯受体提供指导，从而在新的有用方向上促进宿主-客体化学。以及它们在离子识别，传感和逻辑门构造中的可能应用将被详细介绍。希望这篇综述将为设计和制备具有改进的识别特性的新型多组分杯[4]吡咯受体提供指导，从而在新的有用方向上促进宿主-客体化学。