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Review: Remotely controlled magneto-regulation of therapeutics from magnetoelastic gel matrices.
Biotechnology Advances ( IF 12.1 ) Pub Date : 2020-08-18 , DOI: 10.1016/j.biotechadv.2020.107611
Sayan Ganguly 1 , Shlomo Margel 1
Affiliation  

Surface active magnetic nanoparticles especially superparamagnetic iron oxides are already occupying a major domain in medical therapeutics. Arresting of these magnetic nanoparticles into polymer hydrogel is a spatial assembly of nanoparticles that serves the precise delivery of drug molecules. Magnetic hydrogels are very less cultured area still in the biomedical field. This review embraces how the external magnetic field (either static or oscillating) affects the payload release from the hydrogel matrix and their magneto-regulative deformation. Besides these, we also discussed how the ferrosponge and biphasic ferrogel based scaffold type systems impact over the release kinetics and tunability of drug release behaviours.



中文翻译:

综述:磁弹性凝胶基质对治疗剂的遥控磁调节。

表面活性磁性纳米粒子,特别是超顺磁性氧化铁已经在医学治疗领域占据了主要领域。将这些磁性纳米颗粒捕集到聚合物水凝胶中是纳米颗粒的空间组装,可精确递送药物分子。磁性水凝胶在生物医学领域中的培养面积很少。这篇综述涵盖了外部磁场(静态或振荡)如何影响水凝胶基质中的有效负载释放及其磁调节变形。除此之外,我们还讨论了基于铁海绵体和双相铁凝胶的支架类型系统如何影响药物释放行为的释放动力学和可调性。

更新日期:2020-08-18
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