To investigate the effects of the Dejian mind-body intervention (DMBI), on depressive symptoms and electroencephalography (EEG) changes in relation to emotional processing in patients with depression. Seventy-five age-, gender-, and education-matched participants with depression were randomly assigned to receive either Cognitive Behavior Therapy (CBT) or DMBI or were placed in a control group. Overall depressive syndrome, specific mood-related symptoms (Hamilton Psychiatric Rating Scale for Depression, Beck Depression Inventory), and EEG data were collected individually during a resting state and during affective image viewing before and after 10 weeks of intervention. After intervention, both the DMBI and CBT groups showed significantly reduced levels of overall depressive syndrome and mood-related symptoms (Ps ≤ 0.002) than the control group. In addition, the DMBI group demonstrated a significantly greater extent of elevation in fronto-posterior EEG theta coherence on the right hemisphere when viewing different mood-induction (neutral, positive, and negative) stimuli than the CBT and control groups (Ps < 0.03). The elevated intra-right fronto-posterior coherence when viewing mood-induction stimuli correlated with improved mood levels after the intervention (Ps < 0.05). Our findings also showed that, only in the DMBI group, there was a significant suppression of theta source activity at the posterior and subcortical brain regions that are known to mediate negative emotional responses and the self-absorbed mode of thinking. The findings of reduced depressive symptoms and elevated frontoposterior coherence suggest that the DMBI can enhance emotional control in depression.

研究德健心身干预（DMBI）对抑郁症患者抑郁症状和脑电图（EEG）变化与情绪处理相关的影响。75 名年龄、性别和教育匹配的抑郁症参与者被随机分配接受认知行为疗法 ( CBT ) 或DMBI，或被置于对照组。总体抑郁综合征、特定的情绪相关症状（汉密尔顿抑郁症精神病评定量表、贝克抑郁量表）和脑电图数据分别在静息状态和干预 10 周前后的情感图像查看期间收集。干预后，DMBI和与对照组相比，CBT组的整体抑郁综合征和情绪相关症状水平显着降低（P s ≤ 0.002）。此外，DMBI组表现出升高的在一个显著更大程度额后EEG THETA相干性上观看比不同情绪诱导（中性，阳性和阴性）的刺激时右半球CBT组和对照组（P小号<0.03 ）。在观察情绪诱导刺激时，右前前后侧一致性升高与干预后情绪水平的改善相关（P s < 0.05）。我们的研究结果还表明，只有在DMBI组中，后部和皮质下大脑区域的 theta 源活动受到显着抑制，这些区域已知可调节负面情绪反应和自我专注的思维模式。抑郁症状减轻和额后一致性升高的发现表明DMBI可以增强抑郁症的情绪控制。