OBJECTIVE Motivation deficits remain an unmet treatment need in schizophrenia. Recent research has identified mechanisms underlying motivation deficits (i.e., impaired effort-cost computations, reduced future reward-value representation maintenance) that may be effective treatment targets to improve motivation. This study tested the feasibility and preliminary effectiveness of Mobile Enhancement of Motivation in Schizophrenia (MEMS), an intervention that leverages mobile technology to target these mechanisms with text messages. METHOD Fifty-six participants with a schizophrenia-spectrum disorder were randomized to MEMS (n = 27) or a control condition (n = 29). All participants set recovery goals to complete over 8 weeks. Participants in the MEMS group additionally received personalized, interactive text messages on their personal cellphones each weekday. RESULTS Retention and engagement in MEMS were high: 92.6% completed 8 weeks of MEMS, with an 86.1% text message response rate, and 100% reported being satisfied with the text messages. Compared to participants in the control condition, the participants in the MEMS condition had significantly greater improvements in interviewer-rated motivation and anticipatory pleasure and attained significantly more recovery-oriented goals at 8 weeks. There were no significant group differences in purported mechanisms (performance-based effort-cost computations and future reward-value representations) or in self-reported motivation, quality of life, or functioning. CONCLUSION Results demonstrate that MEMS is feasible as a brief, low-intensity mobile intervention that could effectively improve some aspects of motivation (i.e., initiation and maintenance of goal-directed behaviors) and recovery goal attainment for those with schizophrenia-spectrum disorders. More work is needed with larger samples and to understand the mechanisms of change in MEMS. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

中文翻译：

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移动增强精神分裂症的动机：一项针对动机缺陷的个性化短信干预的试点随机对照试验。

目标动机缺陷仍然是精神分裂症中未满足的治疗需求。最近的研究已经确定了动机缺陷的潜在机制（即，努力成本计算受损，未来奖励价值表示维护减少）可能是提高动机的有效治疗目标。本研究测试了移动增强精神分裂症动机 (MEMS) 的可行性和初步有效性，MEMS 是一种利用移动技术通过文本消息针对这些机制的干预措施。方法 56 名患有精神分裂症谱系障碍的参与者被随机分配到 MEMS (n = 27) 或对照条件 (n = 29)。所有参与者都设定了要在 8 周内完成的恢复目标。MEMS 组的参与者还获得了个性化的、每个工作日在他们的个人手机上发送互动短信。结果 MEMS 的保留率和参与度很高：92.6% 的人完成了 8 周的 MEMS，短信回复率为 86.1%，100% 的人表示对短信感到满意。与控制条件下的参与者相比，MEMS 条件下的参与者在面试官评价的动机和预期愉悦方面有显着更大的改善，并且在 8 周时实现了明显更多的以恢复为导向的目标。在声称的机制（基于绩效的努力成本计算和未来奖励价值表示）或自我报告的动机、生活质量或功能方面没有显着的群体差异。结论 结果证明 MEMS 是可行的，低强度移动干预可以有效改善精神分裂症谱系障碍患者某些方面的动机（即目标导向行为的启动和维持）和恢复目标的实现。需要更多的工作来处理更大的样本并了解 MEMS 的变化机制。（PsycInfo 数据库记录 (c) 2020 APA，保留所有权利）。