An efficient cobalt-catalyzed, indium-mediated difunctionalization of iodoalkyl-tethered unactivated alkenes via a cyclization/cross-coupling sequence was developed. The reactions proceeded effectively with wide functional group tolerance, leading to a wide variety of cyclic compounds, including cyclopentane, furan, pyrrolidine, octahydro-1H-indene, octahydro-benzofuran, hexahydro-4H-furo[2,3-b]pyran, and hexahydro-furo[2,3-b]furan, which are pivotal cores widely found in pharmaceutical and bioactive compounds.

中文翻译：

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通过分子内环化和随后的钯催化与芳基卤化物的交叉偶联反应，实现碘化烷基连接的未活化烯烃的铟介导的双官能化

通过环化/交叉偶联序列，开发了一种有效的钴催化，铟介导的碘代烷基连接的未活化烯烃的双官能双官能化。反应在宽的官能团耐受性下有效地进行，产生了多种环状化合物，包括环戊烷，呋喃，吡咯烷，八氢-1 H-茚，八氢苯并呋喃，六氢-4 H-呋喃[2,3- b ]吡喃和六氢呋喃[2,3- b ]呋喃，它们是在药物和生物活性化合物中广泛发现的关键核心。