Adequate knowledge and safe practice of infection prevention among healthcare providers are vital to prevent nosocomial infections. Thus, this study aimed to assess the level of knowledge and practices of healthcare providers towards infection prevention and its associated factors in the health facilities of Wogdie District, Northern Ethiopia. Institution based cross-sectional study was conducted among 171 healthcare providers who were selected by a simple random sampling technique. Data were collected using interviewer-administered questionnaire. Multivariable logistic regression was performed to identify factors associated with knowledge and practice of infection prevention. About 70.8 and 55.0% of healthcare providers had adequate knowledge and safe practice of infection prevention respectively. Having infection prevention guideline (AOR = 3.65, 95% CI; 1.26, 10.54), taking infection prevention training (AOR = 2.2, 95% CI; 1.01, 4.75), having five years or more work experience (AOR = 1.52:95%CI; 1.13, 4.51), and working in maternity unit (AOR = 1.67:95%CI; 1.38–5.23) were positively associated with adequate knowledge of infection prevention. The odds of safe practice were higher in participants who received infection prevention training (AOR: 2.4; 95% CI; 1.01, 4.75) but lower among healthcare providers who are working in the facility which has no continuous water supply (AOR = 0.48:95% CI; 0.21, 0.83). A significant proportion of healthcare providers had inadequate knowledge and unsafe practice of infection prevention. To improve healthcare worker’s knowledge of infection prevention, adequate pre-service as well as on job training should be given.

中文翻译：

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2019 年埃塞俄比亚东北部沃格迪区初级卫生保健单位医疗保健提供者的感染预防知识、实践及其相关因素：一项横断面研究。

医疗保健提供者足够的感染预防知识和安全实践对于预防院内感染至关重要。因此，本研究旨在评估埃塞俄比亚北部沃格迪区卫生设施中医疗保健提供者对感染预防及其相关因素的知识和实践水平。对通过简单随机抽样技术选出的 171 名医疗保健提供者进行了基于机构的横断面研究。使用访谈员管理的问卷收集数据。进行多变量逻辑回归以确定与感染预防知识和实践相关的因素。约 70.8% 和 55.0% 的医疗保健提供者分别拥有足够的感染预防知识和安全实践。有感染预防指南（AOR = 3.65，95% CI；1.26，10.54），接受过感染预防培训（AOR = 2.2，95% CI；1.01，4.75），有五年或以上工作经验（AOR = 1.52：95%） CI; 1.13, 4.51) 和在产科病房工作 (AOR = 1.67:95%CI; 1.38–5.23) 与足够的感染预防知识呈正相关。接受过感染预防培训的参与者的安全实践几率较高（AOR：2.4；95% CI；1.01，4.75），但在没有持续供水的设施中工作的医疗保健提供者则较低（AOR = 0.48:95） % CI；0.21，0.83）。很大一部分医疗保健提供者缺乏足够的感染预防知识和不安全的做法。为了提高医护人员的感染预防知识，应给予充分的上岗前和在岗培训。