Background: Emerging studies manifested that exosomal RNAs had pivotal roles in human cancer therapies. This article aimed to research the regulatory mechanism of exosomal circRNA-plasmacytoma variant translocation 1 (circ-PVT1) in cisplatin (DDP) resistance of gastric cancer (GC).

中文翻译：

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外泌体衍生的 Circ-PVT1 通过 miR-30a-5p/YAP1 轴调节胃癌细胞中的自噬、侵袭和凋亡，从而导致顺铂耐药

背景：新兴研究表明，外泌体 RNA 在人类癌症治疗中具有关键作用。本文旨在研究外泌体circRNA-浆细胞瘤变异易位1（circ-PVT1）在胃癌（GC）顺铂（DDP）耐药中的调控机制。