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Rumphellolide K, a Novel C-3/8 Ether Linkage Caryophyllane from
Heterocycles ( IF 0.8 ) Pub Date : 2020-07-06 , DOI: 10.3987/com-20-14299 Ping-Jyun Sung , Tsong-Long Hwang , Hsu-Ming Chung , Yu-Ming Chang , Wei-Hsien Wang , Jih-Jung Chen
Heterocycles ( IF 0.8 ) Pub Date : 2020-07-06 , DOI: 10.3987/com-20-14299 Ping-Jyun Sung , Tsong-Long Hwang , Hsu-Ming Chung , Yu-Ming Chang , Wei-Hsien Wang , Jih-Jung Chen
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Chemical examination of Rumphella antipathes, collected in the waters of Taiwan, led to the isolation of a novel caryophyllane sesquiterpenoid, rumphellolide K (1), with a C-3/8 ether linkage. The structure of 1 was established by spectroscopic analysis and this compound displayed inhibitory effects on the generation of superoxide anions and the release of elastase by human neutrophils.
更新日期：2020-07-06
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