Regio- and stereoselective decarboxylative aldol reactions of a 1,3-acetonedicarboxylic acid monoester were achieved using an aminobenzothiadiazine organocatalyst. The products were obtained with perfect regioselectivity and moderate to good enantioselectivity using various aromatic aldehydes. Subsequently, the thus obtained adducts were efficiently converted into various chiral building blocks.

中文翻译：

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双功能苯并噻二嗪催化的区域-

1,3-丙酮二羧酸单酯的区域和立体选择性脱羧醛醇缩合反应是使用氨基苯并噻二嗪有机催化剂实现的。使用各种芳族醛以完美的区域选择性和中等至良好的对映选择性获得产物。随后，将如此获得的加合物有效地转化为各种手性结构单元。