The development of photo-polymerizable ferrous sulfate liposomes has been perused for iron fortification of food. Iron fortification is accompanied by several limitations that reduce its quality as it provokes sensory problems due to the oxidation of Fe²⁺ into Fe³⁺. To overcome such undesirable effects and improve the bioavailability of iron, photo-polymerizable 1,2-bis(10,12-tricosadiynoyl)-sn-glycero-3-phosphocholine (DC_8,9PC) phospholipids have been employed as iron delivery system. DC_8,9PC possesses diacetylene groups that undergo intramolecular cross-linking following UV treatment, resulting in enhanced stability, high encapsulation efficiency (~91%) without inducing sensory changes during milk fortification, along with less oxidation and con-tent leakage after long term storage in ethanol. Furthermore, polymeric Fe-DC_8,9PC liposomes present high in vivo iron bioavailability in hemoglobin (Hb)-repletion study in rats, with no indications of toxicity examined by hematoxylin–eosin test. This methodology offers great promise for a simple, reliable, cost-effective, and robust platform for treating iron deficiency anemia, seeking to bring its application toward market.

光聚合硫酸亚铁脂质体的开发已被用于食品的铁强化。铁强化伴随着一些限制，这些限制降低了其质量，因为它会由于 Fe ²⁺氧化成 Fe ³⁺而引起感官问题。为了克服这种不良影响并提高铁的生物利用度，可光聚合的 1,2-双（10,12-二十碳二炔酰基）-sn-甘油-3-磷酸胆碱（DC _8,9 PC）磷脂已被用作铁输送系统. 直流_8,9PC 具有二乙炔基团，可在紫外线处理后进行分子内交联，从而提高稳定性、高封装效率 (~91%)，而不会在牛奶强化过程中​​引起感官变化，并在乙醇中长期储存后减少氧化和含量泄漏. 此外，聚合物 Fe-DC _8,9 PC 脂质体在大鼠血红蛋白 (Hb) 补充研究中表现出较高的体内铁生物利用度，苏木精-伊红试验未发现毒性迹象。这种方法为治疗缺铁性贫血的简单、可靠、具有成本效益和强大的平台提供了广阔的前景，并寻求将其应用推向市场。