Coronavirus Disease 2019 (COVID-19), caused by SARS-CoV-2, is a disaster due to not only its psychosocial impact but it also to its direct effects on the brain. The latest evidence suggests it has neuroinvasive mechanisms, in addition to neurological manifestations, and as seen in past pandemics, long-term sequelae are expected. Specific and well-structured interventions are necessary, and that's why it's important to ensure a continuity between primary care, emergency medicine, and psychiatry. Evidence shows that 2003 SARS (Severe Acute Respiratory Syndrome) survivors developed persistent psychiatric comorbidities after the infection, in addition to Chronic Fatigue Syndrome. A proper stratification of patients according not only to psychosocial factors but also an inflammatory panel and SARS-Cov-2's direct effects on the central nervous system (CNS) and the immune system, may improve outcomes. The complexity of COVID-19's pathology and the impact on the brain requires appropriate screening that has to go beyond the psychosocial impact, taking into account how stress and neuroinflammation affects the brain. This is a call for a clinical multidisciplinary approach to treat and prevent Sars-Cov-2 mental health sequelae.

由 SARS-CoV-2 引起的 2019 冠状病毒病 (COVID-19) 是一场灾难，不仅因为它对社会心理产生影响，还因为它对大脑的直接影响。最新证据表明，除了神经系统表现之外，它还具有神经侵袭机制，并且正如过去的大流行中所见，预计会产生长期后遗症。具体且结构良好的干预措施是必要的，这就是为什么确保初级保健、急诊医学和精神病学之间的连续性很重要。有证据表明，2003 年 SARS（严重急性呼吸系统综合症）幸存者除了慢性疲劳综合症外，在感染后还出现了持续的精神合并症。不仅根据心理社会因素，而且根据炎症组和 SARS-Cov-2 对中枢神经系统 (CNS) 和免疫系统的直接影响对患者进行适当分层，可能会改善结果。 COVID-19 病理学的复杂性以及对大脑的影响需要进行适当的筛查，筛查必须超越社会心理影响，同时考虑到压力和神经炎症对大脑的影响。呼吁采取临床多学科方法来治疗和预防 Sars-Cov-2 心理健康后遗症。