Single exercise stress reduces central neurotrophins levels and adenosine A1 and A2 receptors expression, but does not revert opioid‐induced hyperalgesia in rats,International Journal of Developmental Neuroscience

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Single exercise stress reduces central neurotrophins levels and adenosine A1 and A2 receptors expression, but does not revert opioid‐induced hyperalgesia in rats
International Journal of Developmental Neuroscience ( IF 1.8 ) Pub Date : 2020-09-05 , DOI: 10.1002/jdn.10059
Liciane Fernandes Medeiros _{1,

2} , Éllen Almeida Nunes _{1,

3} , Bettega Costa Lopes _{1,

3} , Andressa de Souza _{1,

2,

4} , Angélica Regina Cappellari ₅ , Joice Soares de Freitas ₁ , Isabel Cristina de Macedo ₁ , Jonnsin Kuo ₁ , Stefania Giotti Cioato ₁ , Ana Maria de Oliveira Battastini ₆ , Wolnei Caumo ₄ , Iraci L S Torres _{1,

3,

4}

Affiliation

This study assessed the effects of an acute stress model upon the long‐term hyperalgesia induced by repeated morphine administration in neonatal rats. We also evaluated neurotrophins and cytokines levels; expressions of adenosine and acetylcholine receptors, and acetylcholinesterase enzyme at the spinal cord.

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