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Peanut Allergy Diagnosis- a 2020 Practice Parameter Update, Systematic Review, and GRADE Analysis.
Journal of Allergy and Clinical Immunology ( IF 11.4 ) Pub Date : 2020-08-15 , DOI: 10.1016/j.jaci.2020.07.031
Matthew Greenhawt 1 , Marcus Shaker 2 , Julie Wang 3 , John J Oppenheimer 4 , Scott Sicherer 3 , Corinne Keet 5 , Keri Swaggart 6 , Matthew Rank 7 , Jay M Portnoy 8 , Jonathan Bernstein 9 , Derek K Chu 10 , Chitra Dinakar 11 , David Golden 12 , Carolyn Horner 13 , David M Lang 14 , Eddy S Lang 15 , David A Khan 16 , Jay Lieberman 17 , David Stukus 18 , Dana Wallace 19
Affiliation  

Given the burden of disease and the consequences of a diagnosis of peanut allergy, it is important that peanut allergy be accurately diagnosed so that an appropriate treatment plan can be developed. However, a test that indicates there is peanut sensitization present (eg, a “positive” test) is not always associated with clinical reactivity. This practice parameter addresses the diagnosis of IgE-mediated peanut allergy, both in children and adults, as pertaining to 3 fundamental questions, and based on the systematic reviews and meta-analyses, makes recommendations for the clinician who is evaluating a patient for peanut allergy. These questions relate to when diagnostic tests should be completed, which diagnostic tests to utilize, and the utility (or lack thereof) of diagnostic testing to predict the severity of a future allergic reaction to peanut.



中文翻译:

花生过敏诊断-2020年实践参数更新,系统评价和GRADE分析。

考虑到疾病负担和花生过敏诊断的后果,重要的是准确诊断花生过敏,以便制定适当的治疗计划。但是,表明存在花生过敏的检测(例如“阳性”检测)并不总是与临床反应性相关。该实践参数涉及3个基本问题,涉及儿童和成人IgE介导的花生过敏的诊断,并基于系统的回顾和荟萃分析,为正在评估患者花生过敏的临床医生提供建议。这些问题涉及何时应完成诊断测试,要使用哪些诊断测试,

更新日期:2020-08-15
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