Background: Potassium permanganate is a green and versatile industrial oxidizing agent. Due to its high oxidizing ability, it has received considerable attention and has been extensively used for many years for the synthesis, identification, and determination of inorganic and organic compounds.

Objective: Potassium permanganate is one of the most applicable oxidants, which has been applied in a number of processes in several industries. Furthermore, it has been widely used in analytical pharmacy to develop analytical methods for pharmaceutically active compounds using chemiluminescence and spectrophotometric techniques.

Results: This review covers the importance of potassium permanganate over other common oxidants used in pharmaceuticals and reported its extensive use and analytical applications using direct, indirect and kinetic spectrophotometric methods in different pharmaceutical formulations and biological samples. Chemiluminescent applications of potassium permanganate in the analyses of pharmaceuticals using flow and sequential injection techniques are also discussed.

Conclusion: This review summarizes the extensive use of potassium permanganate as a chromogenic and chemiluminescent reagent in the analyses of pharmaceutically active compounds to develop spectrophotometric and chemiluminescence methods since 2000.

背景：高锰酸钾是一种绿色且用途广泛的工业氧化剂。由于其高氧化能力，因此受到了广泛的关注，并已广泛用于无机和有机化合物的合成，鉴定和测定。

目标：高锰酸钾是最适用的氧化剂之一，已在多个行业的许多过程中使用。此外，它已被广泛用于分析药学，以开发使用化学发光和分光光度技术的药物活性化合物的分析方法。

结果：这篇综述涵盖了高锰酸钾相对于药物中使用的其他常见氧化剂的重要性，并报告了其在不同药物制剂和生物样品中使用直接，间接和动力学分光光度法的广泛应用和分析应用。还讨论了高锰酸钾在使用流动和顺序注射技术进行药物分析中的化学发光应用。

结论：本综述总结了自2000年以来，高锰酸钾作为发色和化学发光试剂在分析药物活性化合物以开发分光光度法和化学发光方法中的广泛应用。