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Silk-Based Composite Scaffolds for Tissue Engineering Applications
Industrial & Engineering Chemistry Research ( IF 3.8 ) Pub Date : 2020-08-12 , DOI: 10.1021/acs.iecr.0c02195
Saloni Tandon 1 , Balasubramanian Kandasubramanian 2 , Sobhy M. Ibrahim 3
Affiliation  

Tissue engineering is an interdisciplinary field that aims toward the repair of the tissues and organs by bringing together the chemists, material scientists, and biologists to work in coordination for a better understanding of cell–polymer interactions. The leading challenge in the field of tissue engineering is to mimic the naturally occurring extracellular matrix due to which scaffold engineering has become the central area of research in this field. Various materials have been investigated for the fabrication of scaffolds; silk-based composites are among the most promising materials because of their secure processing, adequate mechanical strength, biodegradability, biocompatibility, hemocompatibility, and oxygen and water permeability. This review extensively focuses on the silk-based composite scaffolds, their fabrication, sterilization, and applications in tissue engineering.

中文翻译:

用于组织工程应用的基于丝绸的复合支架

组织工程学是一个跨学科领域,旨在通过组织化学家,材料科学家和生物学家共同努力,以更好地了解细胞与聚合物之间的相互作用,从而修复组织和器官。组织工程领域的主要挑战是模拟天然存在的细胞外基质,因此支架工程已成为该领域研究的中心领域。已经研究了各种材料来制造支架。丝绸基复合材料由于其安全的加工,足够的机械强度,生物降解性,生物相容性,血液相容性以及氧气和水的渗透性而成为最有前途的材料。这篇评论主要针对基于丝绸的复合材料支架,其制造,灭菌,
更新日期:2020-10-07
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