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Biosynthesis of Metal Nanoparticles from Leaves of Ficus palmata and Evaluation of Their Anti-inflammatory and Anti-diabetic Activities.
Biochemistry ( IF 2.9 ) Pub Date : 2020-08-14 , DOI: 10.1021/acs.biochem.0c00388
Satish C Sati 1 , Gurpreet Kour 1 , Ankit S Bartwal 1 , Maneesha D Sati 2
Affiliation  

Metal nanoparticles (AgNPs and ZnONPs) were synthesized using a green methodology with the green leaves extract of the Bedu (Ficus palmata) tree as a reducing agent and the support of natural fibers. The synthesized AgNPs and ZnONPs were characterized by several techniques, including ultraviolet–visible spectral analysis, powder X-ray diffraction crystal analysis, scanning electron microscopy, EDAX, transmission electron microscopy, and Fourier transform infrared spectroscopy, which confirmed that the synthesized particles are in the nano range (1–100 nm), i.e., 30 nm for AgNPs with polydispersity and a spherical shape, whereas the average size of synthesized ZnONPs is 34 nm and they seem to exhibit a distorted spherical shape. The results of thermogravimetric analysis confirmed a weight loss of 18.02% for AgNPs under exothermic conditions due to the desorption of water, and ZnONPs show weight loss between 265 and 500 °C. Both synthesized MNPs are highly thermally stable. Anti-inflammatory and anti-diabetic studies of metal NPs have been evaluated. The AgNPs and ZnONPs of F. palmata leaves showed remarkably highly potent activity for respective strains. In vitro anti-diabetic activity was found for inhibition of α-amylases and α-glucosidases by synthesized silver nanoparticles.

中文翻译:

棕榈榕叶片中金属纳米颗粒的生物合成及其抗炎和抗糖尿病活性的评价。

金属纳米粒子(的AgNPs和ZnONPs)用绿色的方法与绿叶合成提取Bedu(的榕掌叶)树木作为还原剂和天然纤维的载体。用紫外可见光谱分析,粉末X射线衍射晶体分析,扫描电子显微镜,EDAX,透射电子显微镜和傅里叶变换红外光谱等几种技术对合成的AgNPs和ZnONPs进行了表征,证实了合成的颗粒处于纳米范围(1–100 nm),即具有多分散性和球形的AgNPs为30 nm,而合成的ZnONP的平均尺寸为34 nm,它们似乎呈现出扭曲的球形。热重分析的结果证实,由于水的解吸,放热条件下AgNPs的重量损失为18.02%,而ZnONPs的重量损失为265至500°C。两种合成的MNP都是高度热稳定的。已评估了金属NP的抗炎和抗糖尿病研究。AgNPs和ZnONPs棕榈F.叶片对各个菌株均显示出非常高的活性。发现了通过合成的银纳米颗粒抑制α-淀粉酶和α-葡萄糖苷酶的体外抗糖尿病活性。
更新日期:2020-08-25
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