Abstract Mathematical immunology is the branch of mathematics dealing with the application of mathematical methods and computational algorithms to explore the structure, dynamics, organization and regulation of the immune system in health and disease. We review the conceptual and mathematical foundation of modelling in immunology formulated by Guri I. Marchuk. The current frontier studies concerning the development of multiscale multiphysics integrative models of the immune system are presented.

中文翻译：

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数学免疫学：从现象学到多物理场建模

摘要 数学免疫学是数学的一个分支，涉及应用数学方法和计算算法来探索健康和疾病中免疫系统的结构、动力学、组织和调节。我们回顾了 Guri I. Marchuk 制定的免疫学建模的概念和数学基础。介绍了当前关于开发免疫系统多尺度多物理场综合模型的前沿研究。