Medicinal importance of Embelia ribes Burm f. is known since ancient time. Its berries are the main ingredient in Vidanga’ or ‘Baibidanga’—a component of ayurvedic formulations and possess medicinal properties such as antihelmintic, anticancer, neuroprotective and antidiabetic. Studies were conducted on phytochemicals, antioxidant activities, extraction efficiency of embelin from ten genotypes. Methanolic extract of berries from Nagavelli accession exhibited the highest total phenolic content (18.18 ± 0.14 mg GAE/g DW); whereas, ethanolic extract showed highest total flavonoid content (8.35 ± 0.20 mg RE/g DW). The antioxidant activities (AOA) were assessed and noted that ethanolic and methanolic extracts of berries from Nagavelli (NAG) accession revealed highest activities in terms of DPPH radical scavenging activity (67.48 ± 0.17%) and FRAP (66.73 ± 0.60 mg Fe(II)/g DW), respectively. In AOA analysis, berries extracted with different solvents were positively correlated with TPC. Principal component analysis revealed TPC and TFC were the most influencing components for strong antioxidant activities in E. ribes. Reverse phase high performance liquid chromatography (RP-HPLC) was used to quantify embelin content and its optimize extraction using various methods. In the preliminary studies, berries from NAG accession revealed highest (1.770%) embelin content. Further, berries from NAG accession were subjected to various extraction methods and found three fold increase (5.08%) in embelin content in microwave assisted extraction (90 s). Present study suggested that NAG accession found to be a promising source of natural antioxidants and embelin that can be used in pharmaceutical industries.

中文翻译：

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植物化学分析、抗氧化活性以及不同基因型 Embelia ribes Burm f. 中余甘子素的优化提取：一种来自印度西高止山脉的木本药用攀缘植物。


余甘子的药用价值 Burm f．自古以来就众所周知。它的浆果是 Vidanga 或 Baibidanga 的主要成分，它是阿育吠陀配方的一个组成部分，具有抗蠕虫、抗癌、神经保护和抗糖尿病等药用特性。对十个基因型的嵌入素的植物化学物质、抗氧化活性、提取效率进行了研究。 Nagavelli 浆果的甲醇提取物表现出最高的总酚含量（18.18 ± 0.14 mg GAE/g DW）；而乙醇提取物的总黄酮含量最高（8.35 ± 0.20 mg RE/g DW）。对抗氧化活性 (AOA) 进行了评估，发现 Nagavelli (NAG) 浆果的乙醇和甲醇提取物在 DPPH 自由基清除活性 (67.48 ± 0.17%) 和 FRAP (66.73 ± 0.60 mg Fe(II)) 方面显示出最高活性。 /g DW），分别。在AOA分析中，不同溶剂提取的浆果与TPC呈正相关。主成分分析表明，TPC和TFC是大肠杆菌强抗氧化活性影响最大的成分。茶藨。使用反相高效液相色谱 (RP-HPLC) 来量化嵌入素含量并使用各种方法优化其提取。在初步研究中，NAG 种质的浆果显示出最高的嵌入素含量（1.770%）。此外，对来自 NAG 的浆果进行了各种提取方法，发现微波辅助提取（90 秒）中嵌入素含量增加了三倍（5.08%）。目前的研究表明，NAG 是一种有前景的天然抗氧化剂和嵌入素来源，可用于制药工业。