Medicinal importance of Embelia ribes Burm f. is known since ancient time. Its berries are the main ingredient in Vidanga’ or ‘Baibidanga’—a component of ayurvedic formulations and possess medicinal properties such as antihelmintic, anticancer, neuroprotective and antidiabetic. Studies were conducted on phytochemicals, antioxidant activities, extraction efficiency of embelin from ten genotypes. Methanolic extract of berries from Nagavelli accession exhibited the highest total phenolic content (18.18 ± 0.14 mg GAE/g DW); whereas, ethanolic extract showed highest total flavonoid content (8.35 ± 0.20 mg RE/g DW). The antioxidant activities (AOA) were assessed and noted that ethanolic and methanolic extracts of berries from Nagavelli (NAG) accession revealed highest activities in terms of DPPH radical scavenging activity (67.48 ± 0.17%) and FRAP (66.73 ± 0.60 mg Fe(II)/g DW), respectively. In AOA analysis, berries extracted with different solvents were positively correlated with TPC. Principal component analysis revealed TPC and TFC were the most influencing components for strong antioxidant activities in E. ribes. Reverse phase high performance liquid chromatography (RP-HPLC) was used to quantify embelin content and its optimize extraction using various methods. In the preliminary studies, berries from NAG accession revealed highest (1.770%) embelin content. Further, berries from NAG accession were subjected to various extraction methods and found three fold increase (5.08%) in embelin content in microwave assisted extraction (90 s). Present study suggested that NAG accession found to be a promising source of natural antioxidants and embelin that can be used in pharmaceutical industries.

中文翻译：

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从 Embelia ribes Burm f. 的不同基因型中提取 embelin 的植物化学分析、抗氧化活性和优化提取：来自印度西高止山脉的木质药用攀缘植物。

Embelia ribes 的药用价值伯姆 f. 自古为人所知。它的浆果是 Vidanga' 或 'Baibidanga' 的主要成分——阿育吠陀配方的一种成分，具有抗蠕虫、抗癌、神经保护和抗糖尿病等药用特性。对 10 个基因型的 embelin 的植物化学物质、抗氧化活性和提取效率进行了研究。Nagavelli 浆果的甲醇提取物表现出最高的总酚含量 (18.18 ± 0.14 mg GAE/g DW)；而乙醇提取物的总黄酮含量最高 (8.35 ± 0.20 mg RE/g DW)。评估了抗氧化活性 (AOA)，并注意到 Nagavelli (NAG) 浆果的乙醇和甲醇提取物在 DPPH 自由基清除活性 (67.48 ± 0.17%) 和 FRAP (66.73 ± 0.60 mg Fe(II)) 方面具有最高活性/g DW), 分别。在 AOA 分析中，不同溶剂提取的浆果与 TPC 呈正相关。主成分分析表明，TPC 和 TFC 是对强抗氧化活性影响最大的成分。乙。肋骨。反相高效液相色谱 (RP-HPLC) 用于量化 embelin 含量并使用各种方法优化提取。在初步研究中，来自 NAG 种质的浆果显示最高 (1.770%) embelin 含量。此外，来自 NAG 的浆果经过各种提取方法，发现微波辅助提取（90 秒）中的 embelin 含量增加了三倍（5.08%）。目前的研究表明，NAG 加入被发现是可用于制药行业的天然抗氧化剂和 embelin 的有希望的来源。