Biofilms are structured microbial communities of single or multiple populations in which microbial cells adhere to a surface and get embedded in extracellular polymeric substances (EPS). This review attempts to explain biofilm architecture, development phases, and forces that drive bacteria to promote biofilm mode of growth. Bacterial chemical communication, also known as Quorum sensing (QS), which involves the production, detection, and response to small molecules called autoinducers, is highlighted. The review also provides a brief outline of interspecies and intraspecies cell–cell communication. Additionally, we have performed docking studies using Discovery Studio 4.0, which has enabled our understanding of the prominent interactions between autoinducers and their receptors in different bacterial species while also scoring their interaction energies. Receptors, such as LuxN (Phosphoreceiver domain and RecA domain), LuxP, and LuxR, interacted with their ligands (AI-1, AI-2, and AHL) with a CDocker interaction energy of − 31.6083 kcal/mole; − 34.5821 kcal/mole, − 48.2226 kcal/mole and − 41.5885 kcal/mole, respectively. Since biofilms are ideal for the remediation of contaminants due to their high microbial biomass and their potential to immobilize pollutants, this article also provides an overview of biofilm-mediated bioremediation.

中文翻译：

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微生物生物膜生态学，群体感应受体-配体相互作用和生物膜介导的生物修复的硅片研究

生物膜是单个或多个群体的结构化微生物群落，其中微生物细胞粘附在表面并嵌入细胞外聚合物 (EPS) 中。这篇综述试图解释生物膜结构、发展阶段和驱动细菌促进生物膜生长模式的力量。强调了细菌化学通讯，也称为群体感应 (QS)，它涉及对称为自诱导剂的小分子的产生、检测和响应。该评论还提供了种间和种内细胞间通讯的简要概述。此外，我们还使用 Discovery Studio 4.0 进行了对接研究，这使我们能够了解不同细菌物种中自诱导剂与其受体之间的显着相互作用，同时也对它们的相互作用能进行评分。受体，例如 LuxN（磷光受体域和 RecA 域）、LuxP 和 LuxR，与其配体（AI-1、AI-2 和 AHL）相互作用，CDocker 相互作用能量为 - 31.6083 kcal/mole；− 34.5821 kcal/mole、− 48.2226 kcal/mole 和 − 41.5885 kcal/mole。由于生物膜具有高微生物量和固定污染物的潜力，因此是污染物修复的理想选择，因此本文还概述了生物膜介导的生物修复。6083 大卡/摩尔；− 34.5821 kcal/mole、− 48.2226 kcal/mole 和 − 41.5885 kcal/mole。由于生物膜具有高微生物量和固定污染物的潜力，因此是污染物修复的理想选择，因此本文还概述了生物膜介导的生物修复。6083 大卡/摩尔；− 34.5821 kcal/mole、− 48.2226 kcal/mole 和 − 41.5885 kcal/mole。由于生物膜具有高微生物量和固定污染物的潜力，因此是污染物修复的理想选择，因此本文还概述了生物膜介导的生物修复。