Coronavirus disease 2019 (COVID-19) characterized by immuno-pathological host responses including pneumonia, lymphopenia, and cytokine storm that leads to severe lung inflammation, developed in acute respiratory distress syndrome (ARDS). In the absence of an effective vaccine or any definitive cure, the use of host-directed therapies is an effective alternative and demanding treatment option in the current pandemic outbreak of COVID-19.

中文翻译：

---

宿主定向疗法：对抗COVID-19的潜在解决方案。

冠状病毒疾病2019（COVID-19）的特征是免疫病理宿主反应，包括导致严重肺部炎症的肺炎，淋巴细胞减少和细胞因子风暴，在急性呼吸窘迫综合征（ARDS）中发展。在没有有效的疫苗或任何确定的治疗方法的情况下，在当前大流行的COVID-19暴发中，使用针对宿主的疗法是一种有效的替代选择，并且要求苛刻的治疗选择。