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Biogenesis of the peptide-derived redox cofactor pyrroloquinoline quinone.
Current opinion in chemical biology Pub Date : 2020-07-27 , DOI: 10.1016/j.cbpa.2020.05.001
Wen Zhu 1 , Judith P Klinman 2
Affiliation  

Pyrroloquinoline quinone (PQQ) is a peptide-derived redox cofactor produced by prokaryotes that also plays beneficial roles in organisms from other kingdoms. We review recent developments on the pathway of PQQ biogenesis, focusing on the mechanisms of PqqE, PqqF/G, and PqqB. These advances may shed light on other, uncharacterized biosynthetic pathways.

中文翻译:


肽衍生的氧化还原辅因子吡咯喹啉醌的生物发生。



吡咯喹啉醌 (PQQ) 是一种由原核生物产生的肽衍生氧化还原辅助因子,在其他界的生物体中也发挥着有益作用。我们回顾了 PQQ 生物发生途径的最新进展,重点关注 PqqE、PqqF/G 和 PqqB 的机制。这些进展可能有助于揭示其他未表征的生物合成途径。
更新日期:2020-07-27
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