Expert Review of Pharmacoeconomics & Outcomes Research ( IF 1.8 ) Pub Date : 2020-08-30 , DOI: 10.1080/14737167.2020.1804873 Isabella de Figueiredo Zuppo 1 , Cristina Mariano Ruas 2 , Helian Nunes de Oliveira 3 , Brian Godman 4, 5, 6, 7 , Saulo Castel 8 , Milton L Wainberg 9 , Edna Afonso Reis 10
ABSTRACT
Background
There is a need to evaluate the health equity of atypical antipsychotics users who obtain their medicines from the Brazilian National Health System (SUS) through the identification of key factors that influence their health status due to concerns with equity of care.
Research design and methods
Cross-sectional study among patients attending state pharmacies in Brazil. Individuals were included if they used atypical antipsychotics, aged ≥18 years, and answered the EQ-5D-3 L questionnaire. Sociodemographic, behavioral, and clinical data were collected. The dependent variable was health status. Associations between the independent variables and the dependent variable were analyzed by adjusting a linear regression model.
Results
Overall, 388 individuals met the eligibility criteria and were included in the analysis. The final multiple linear regression model demonstrated a statistically significant association between VAS and suicide attempts, private care, current antipsychotics, comorbidities, and perceived family support.
Expert Commentary
The study identified several factors both individual and collective that correlate with the health status of atypical antipsychotic users and confirmed the importance of providing medicines for treating psychotic disorders. However, other factors are involved including social support. Our results suggest additional activities and policies are necessary including strategies to address the differences in private and public health care.
中文翻译:
巴西国家卫生系统内的健康公平和非典型抗精神病药物的使用:发现和影响
摘要
背景
有必要通过识别由于关心公平性而影响其健康状况的关键因素,来评估从巴西国家卫生系统 (SUS) 获得药物的非典型抗精神病药物使用者的健康公平性。
研究设计与方法
巴西国家药房患者的横断面研究。如果个人使用非典型抗精神病药物,年龄≥18 岁,并回答了 EQ-5D-3 L 问卷,则被纳入研究。收集了社会人口学、行为学和临床数据。因变量是健康状况。通过调整线性回归模型来分析自变量和因变量之间的关联。
结果
总体而言,388 人符合资格标准并被纳入分析。最终的多元线性回归模型表明,VAS 与自杀未遂、私人护理、当前的抗精神病药物、合并症和感知的家庭支持之间存在统计学上的显着关联。
专家评论
该研究确定了与非典型抗精神病药物使用者的健康状况相关的个人和集体因素,并证实了提供治疗精神病药物的重要性。但是,还涉及其他因素,包括社会支持。我们的结果表明,需要采取额外的活动和政策,包括解决私人和公共医疗保健差异的策略。