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Potential strategies for combating COVID-19.
Archives of Virology ( IF 2.5 ) Pub Date : 2020-08-10 , DOI: 10.1007/s00705-020-04768-3
Saba Shamim 1 , Maryam Khan 1 , Zelal Jaber Kharaba 2 , Munazza Ijaz 1 , Ghulam Murtaza 3
Affiliation  

Coronavirus disease 2019, also known as COVID-19, is caused by a novel coronavirus named severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2. The infection has now catapulted into a full-blown pandemic across the world, which has affected more than 2 million people and has led to approximately 150,000 fatalities all over the world (WHO). In this review, we elaborate all currently available data that shed light on possible methods for treatment of COVID-19, such as antiviral drugs, corticosteroids, convalescent plasma, and potentially effective vaccines. Additionally, ongoing and discontinued clinical trials that have been carried out for validating probable treatments for COVID-19 are discussed. The review also elaborates the prospective approach and the possible advantages of using convalescent plasma and stem cells for the improvement of clinical symptoms and meeting the demand for an instantaneous cure.

中文翻译:

对抗 COVID-19 的潜在策略。

2019 年冠状病毒病,也称为 COVID-19,是由一种名为严重急性呼吸综合征冠状病毒 2 或 SARS-CoV-2 的新型冠状病毒引起的。这种感染现已在全球范围内迅速发展为全面流行病,已影响超过 200 万人,并导致全世界约 150,000 人死亡(世卫组织)。在这篇综述中,我们详细阐述了所有当前可用的数据,这些数据揭示了治疗 COVID-19 的可能方法,例如抗病毒药物、皮质类固醇、恢复期血浆和潜在有效的疫苗。此外,还讨论了为验证 COVID-19 可能的治疗方法而进行的和已停止的临床试验。
更新日期:2020-08-10
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