当前位置: X-MOL 学术J. Bacteriol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Zebrafish models for pathogenic Vibrios.
Journal of Bacteriology ( IF 2.7 ) Pub Date : 2020-11-19 , DOI: 10.1128/jb.00165-20
Dhrubajyoti Nag 1 , Dustin A Farr 1 , Madison G Walton 1 , Jeffrey H Withey 2
Affiliation  

Vibrio is a large and diverse genus of bacteria, of which most are nonpathogenic species found in the aquatic environment. However, a subset of the Vibrio genus includes several species that are highly pathogenic, either to humans or to aquatic animals. In recent years, Danio rerio, commonly known as the zebrafish, has emerged as a major animal model used for studying nearly every aspect of biology, including infectious diseases. Zebrafish are especially useful because the embryos are transparent, larvae are small and facilitate imaging studies, and numerous transgenic fish strains have been constructed. Zebrafish models for several pathogenic Vibrio species have been described, and indeed a fish model is highly relevant for the study of aquatic bacterial pathogens. Here, we summarize the zebrafish models that have been used to study pathogenic Vibrio species to date.

中文翻译:

致病性弧菌的斑马鱼模型。

弧菌是一个庞大而多样的细菌属,其中大多数是在水生环境中发现的非致病性物种。然而,弧菌属的一个子集包括几个对人类或水生动物具有高致病性的物种。近年来,斑马鱼已成为研究生物学几乎各个方面(包括传染病)的主要动物模型。斑马鱼特别有用,因为胚胎是透明的,幼虫很小并且有利于成像研究,并且已经构建了许多转基因鱼品系。已经描述了几种致病性弧菌物种的斑马鱼模型,并且实际上鱼类模型与水生细菌病原体的研究高度相关。在这里,我们总结了迄今为止用于研究致病性弧菌物种的斑马鱼模型。
更新日期:2020-11-19
down
wechat
bug