The process of regeneration describes the full restoration of tissue after destruction from injury or disease. Most mammals show very limited ability for regeneration of adult organs, while vertebrate models of regeneration such as fish and salamanders, allow to study regeneration mechanism of the brain, heart, limbs, retina, and other organs in adults. The regenerative abilities of teleost fish are well documented, but the cellular sources for regeneration, the specificity of source cells for restored cell types, as well as the extent and fidelity of cell replacement are only beginning to be revealed for many regeneration paradigms. Here, we highlight recent analyses of adult neurogenesis and regeneration after injury in teleost fish that address these issues, and we discuss how such analyses can help to evaluate the role of different cells in tissues in the regeneration process.

中文翻译：

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脊椎动物脑再生 - 命运受限的前体细胞类型的社区努力。

再生过程描述了组织在受伤或疾病破坏后的完全恢复。大多数哺乳动物的成体器官再生能力非常有限，而鱼类和蝾螈等再生脊椎动物模型允许研究成体大脑、心脏、四肢、视网膜和其他器官的再生机制。硬骨鱼的再生能力已得到充分证明，但再生的细胞来源、恢复细胞类型的源细胞的特异性以及细胞替代的程度和保真度才刚刚开始在许多再生范例中得到揭示。在这里，我们重点介绍了最近对硬骨鱼损伤后成体神经发生和再生的分析，以解决这些问题，