This article introduces GeMS, a system for music composition informed by synthetic biology. GeMS generates music with simulations of genetic processes, such as transcription, translation, and protein folding, with which biological systems render chains of amino acids from DNA strands. The system comprises the following components: the Miranda machine, the rhythmator, and the pitch processor. The Miranda machine is an abstract Turing-machine-like processor, which manipulates a sequence of DNA symbols according to a set of programming instructions. This process generates a pool of new DNA strands, which are subsequently translated into rhythms. GeMS represents the musical equivalent of amino acids in terms of rhythms, referred to as rhythmic codons. This enables the rhythmator to convert DNA sequences into rhythmic sequences. The pitch processor generates pitches for such rhythmic sequences. It is inspired by the phenomenon of protein folding. The pitch processor considers orientation information of DNA instructions yielded by the Miranda machine in order to activate algorithms for generating pitches. A musical composition, entitled Artibiotics, for percussion ensemble and electronic instruments, is presented to demonstrate the system.

中文翻译：

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具有合成生物学的基因音乐系统

本文介绍了 GeMS，这是一种基于合成生物学的音乐创作系统。GeMS 通过模拟遗传过程（如转录、翻译和蛋白质折叠）生成音乐，生物系统通过这些过程从 DNA 链呈现氨基酸链。该系统包括以下组件：米兰达机器、节奏器和音高处理器。米兰达机是一个抽象的类似图灵机的处理器，它根据一组编程指令操作一系列 DNA 符号。这个过程产生了一个新的 DNA 链池，这些链随后被翻译成节奏。GeMS 代表了氨基酸在韵律方面的音乐等价物，称为韵律密码子。这使节奏器能够将 DNA 序列转换为有节奏的序列。音高处理器为这种有节奏的序列生成音高。它的灵感来自蛋白质折叠现象。音调处理器考虑由米兰达机器产生的 DNA 指令的方向信息，以激活生成音调的算法。展示了一个名为 Artibiotics 的音乐作品，用于打击乐合奏和电子乐器，以演示该系统。