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Recent insights into zebrafish cardiac regeneration.
Current Opinion in Genetics & Development ( IF 3.7 ) Pub Date : 2020-06-26 , DOI: 10.1016/j.gde.2020.05.020
Andrés Sanz-Morejón 1 , Nadia Mercader 1
Affiliation  

In humans, myocardial infarction results in ventricular remodeling, progressing ultimately to cardiac failure, one of the leading causes of death worldwide. In contrast to the adult mammalian heart, the zebrafish model organism has a remarkable regenerative capacity, offering the possibility to research the bases of natural regeneration. Here, we summarize recent insights into the cellular and molecular mechanisms that govern cardiac regeneration in the zebrafish.

中文翻译:

对斑马鱼心脏再生的最新见解。

在人类中,心肌梗塞会导致心室重构,最终发展为心力衰竭,这是全世界死亡的主要原因之一。与成年哺乳动物心脏相比,斑马鱼模型生物具有显着的再生能力,为研究自然再生的基础提供了可能性。在这里,我们总结了最近对控制斑马鱼心脏再生的细胞和分子机制的见解。
更新日期:2020-06-26
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