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Fabrication and validation of reference structures for the localization of subdural standard- and micro-electrodes in MRI.
Journal of Neural Engineering ( IF 3.7 ) Pub Date : 2020-09-17 , DOI: 10.1088/1741-2552/abad7a
Johannes B Erhardt 1, 2 , Thomas Lottner 3 , Cristian F Pasluosta 1 , Isabel Gessner 4 , Sanjay Mathur 4 , Martin Schuettler 5 , Michael Bock 3 , Thomas Stieglitz 1, 2, 6
Affiliation  

Objective. Report simple reference structure fabrication and validate the precise localization of subdural micro- and standard electrodes in magnetic resonance imaging (MRI) in phantom experiments. Approach . Electrode contacts with diameters of 0.3 mm and 4 mm are localized in 1.5 T MRI using reference structures made of silicone and iron oxide nanoparticle doping. The precision of the localization procedure was assessed for several standard MRI sequences and implant orientations in phantom experiments and compared to common clinical localization procedures. Main results. A localization precision of 0.41 ± 0.20 mm could be achieved for both electrode diameters compared to 1.46 ± 0.69 mm that was achieved for 4 mm standard electrode contacts localized using a common clinical standard method. The new reference structures are intrinsically bio-compatible, and they can be detected with currently available feature detection software so that a clinical implementati...

中文翻译:

制造和验证用于在 MRI 中定位硬膜下标准电极和微电极的参考结构。

客观的。报告简单的参考结构制造,并在体模实验中验证硬膜下微电极和标准电极在磁共振成像 (MRI) 中的精确定位。方法 。使用由有机硅和氧化铁纳米颗粒掺杂制成的参考结构,在 1.5 T MRI 中定位直径为 0.3 毫米和 4 毫米的电极触点。在体模实验中评估了几个标准 MRI 序列和植入物方向的定位程序的精度,并与常见的临床定位程序进行了比较。主要结果。与使用常用临床标准方法定位的 4 mm 标准电极触点实现的 1.46 ± 0.69 mm 相比,两种电极直径的定位精度都可以达到 0.41 ± 0.20 mm。
更新日期:2020-09-20
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