Respiratory dysfunction is one of the most debilitating effects of spinal cord injury (SCI) impacting the quality of life of patients and caregivers. In addition, breathing difficulties impact the rehabilitation routine a patient may potentially undergo. Transcutaneous electrical spinal cord neuromodulation (TESCoN) is a novel approach to reactivate and retrain spinal circuits after paralysis. We demonstrate that acute and chronic TESCoN therapy over the cervical spinal cord positively impacts the breathing and coughing ability in a patient with chronic tetraplegia. ln addition, we show that the improved breathing and coughing ability are not only observed in the presence of TESCoN but persisted for a few days after TESCoN was stopped.

中文翻译：

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严重慢性四肢瘫痪后实现呼吸控制：探索性案例研究。


呼吸功能障碍是脊髓损伤 (SCI) 最严重的影响之一，影响患者和护理人员的生活质量。此外，呼吸困难会影响患者可能经历的康复程序。经皮脊髓电神经调节（TESCoN）是一种在瘫痪后重新激活和重新训练脊髓回路的新方法。我们证明，对颈脊髓进行急性和慢性 TESCoN 治疗对慢性四肢瘫痪患者的呼吸和咳嗽能力有积极影响。此外，我们发现呼吸和咳嗽能力的改善不仅在 TESCoN 存在时观察到，而且在 TESCoN 停止后持续几天。