Banana production is severely constrained by many pathogens and pests, particularly where a number of them are co-existing. The use of disease-resistant banana varieties is one of the most effective ways to mitigate the negative impacts of pathogens on banana production. Recent advances in new breeding techniques have the potential to accelerate breeding of banana for disease resistance. The CRISPR/Cas9 based genome editing has emerged as the most powerful tool for crop improvement due to its capability of creating precise alterations in plant genome and trait stacking through multiplexing. Recently, the robust CRISPR/Cas9-based genome editing of banana has been established, which can be applied for developing disease-resistant varieties. This article presents a synopsis of recent advancements and perspectives on the application of genome editing for generating disease-resistant banana varieties. It also summarizes the current status of regulatory requirements for the release of genome-edited crop varieties among different countries.

中文翻译：

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基于CRISPR / Cas9的香蕉基因组编辑以提高抗病能力。

香蕉的生产受到许多病原体和害虫的严重限制，特别是在其中许多病原体和病虫害并存的情况下。抗病香蕉品种的使用是减轻病原体对香蕉生产的负面影响的最有效方法之一。新育种技术的最新进展具有加速抗病香蕉育种的潜力。基于CRISPR / Cas9的基因组编辑已成为作物改良的最强大工具，因为它具有通过多重创建植物基因组和性状堆叠的精确改变的能力。最近，已经建立了基于CRISPR / Cas9的香蕉基因组编辑功能，可用于开发抗病品种。本文介绍了有关基因组编辑在产生抗病香蕉品种中的应用的最新进展和观点。它还总结了不同国家之间发布基因组编辑的作物品种的法规要求的现状。