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Quantification of effects of mean blood pressure and left ventricular mass on noninvasive fast fractional flow reserve
AJP Heart and Circulatory Physiology Pub Date : 2020-07-17 , DOI: 10.1152/ajpheart.00135.2020 Jun-Mei Zhang 1, 2 , Gaurav Chandola 1 , Ru-San Tan 1, 2 , Ping Chai 3 , Lynette L S Teo 3 , Ris Low 1 , John Carson Allen 2 , Weimin Huang 4 , Jiang Ming Fam 1 , Chee Yang Chin 1 , Aaron Sung Lung Wong 1, 2 , Adrian F Low 3 , Ghassan S Kassab 5 , Terrance Chua 1, 2 , Swee Yaw Tan 1, 2 , Soo Teik Lim 1, 2 , Liang Zhong 1, 2
AJP Heart and Circulatory Physiology Pub Date : 2020-07-17 , DOI: 10.1152/ajpheart.00135.2020 Jun-Mei Zhang 1, 2 , Gaurav Chandola 1 , Ru-San Tan 1, 2 , Ping Chai 3 , Lynette L S Teo 3 , Ris Low 1 , John Carson Allen 2 , Weimin Huang 4 , Jiang Ming Fam 1 , Chee Yang Chin 1 , Aaron Sung Lung Wong 1, 2 , Adrian F Low 3 , Ghassan S Kassab 5 , Terrance Chua 1, 2 , Swee Yaw Tan 1, 2 , Soo Teik Lim 1, 2 , Liang Zhong 1, 2
Affiliation
While brachial mean blood pressure (MBP) and left ventricular mass (LVM) measured from CTCA are the two CFD simulation input parameters, their effects on noninvasive fractional flow reserve (FFRB ) have not been systematically investigated. We demonstrate that inaccurate MBP and LVM inputs differing from patient-specific values could result in misclassification of borderline ischemic lesions. This is important in the clinical application of noninvasive FFR in coronary artery disease diagnosis.
中文翻译:
平均血压和左心室质量对无创快速血流储备分数影响的量化
虽然从 CTCA 测量的肱平均血压 (MBP) 和左心室质量 (LVM) 是两个 CFD 模拟输入参数,但它们对无创血流储备分数 (FFR) 的影响乙 )尚未进行系统研究。我们证明,与患者特定值不同的不准确的 MBP 和 LVM 输入可能会导致边界缺血性病变的错误分类。这对于无创FFR在冠心病诊断中的临床应用具有重要意义。
更新日期:2020-07-17
中文翻译:
平均血压和左心室质量对无创快速血流储备分数影响的量化
虽然从 CTCA 测量的肱平均血压 (MBP) 和左心室质量 (LVM) 是两个 CFD 模拟输入参数,但它们对无创血流储备分数 (FFR) 的影响