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Quantification of effects of mean blood pressure and left ventricular mass on noninvasive fast fractional flow reserve
AJP Heart and Circulatory Physiology Pub Date : 2020-07-17 , DOI: 10.1152/ajpheart.00135.2020
Jun-Mei Zhang 1, 2 , Gaurav Chandola 1 , Ru-San Tan 1, 2 , Ping Chai 3 , Lynette L S Teo 3 , Ris Low 1 , John Carson Allen 2 , Weimin Huang 4 , Jiang Ming Fam 1 , Chee Yang Chin 1 , Aaron Sung Lung Wong 1, 2 , Adrian F Low 3 , Ghassan S Kassab 5 , Terrance Chua 1, 2 , Swee Yaw Tan 1, 2 , Soo Teik Lim 1, 2 , Liang Zhong 1, 2
Affiliation  

While brachial mean blood pressure (MBP) and left ventricular mass (LVM) measured from CTCA are the two CFD simulation input parameters, their effects on noninvasive fractional flow reserve (FFRB) have not been systematically investigated. We demonstrate that inaccurate MBP and LVM inputs differing from patient-specific values could result in misclassification of borderline ischemic lesions. This is important in the clinical application of noninvasive FFR in coronary artery disease diagnosis.

中文翻译:

平均血压和左心室质量对无创快速血流储备分数影响的量化

虽然从 CTCA 测量的肱平均血压 (MBP) 和左心室质量 (LVM) 是两个 CFD 模拟输入参数,但它们对无创血流储备分数 (FFR) 的影响)尚未进行系统研究。我们证明,与患者特定值不同的不准确的 MBP 和 LVM 输入可能会导致边界缺血性病变的错误分类。这对于无创FFR在冠心病诊断中的临床应用具有重要意义。
更新日期:2020-07-17
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