In this review, we summarize our recent progress on functionalization of the ammonium C–N bond through a transition-metal-catalysed cross-coupling process. By synergistic utilization of computational and experimental methods, we have successfully developed several new C–N bond cleavage protocols and established new reaction mechanisms. These findings provide new possibilities for transforming naturally abundant chemicals into useful functional molecules in an efficient and selective manner.

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中文翻译：

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通过铵CN键断裂的过渡金属催化交叉偶联反应的发展。

在这篇综述中，我们总结了我们最近通过过渡金属催化的交叉偶联过程在铵化C–N键上取得的进展。通过协同利用计算和实验方法，我们成功开发了几种新的C–N键裂解方案并建立了新的反应机理。这些发现为以高效和选择性的方式将天然丰富的化学物质转化为有用的功能分子提供了新的可能性。

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