Germline mutations are the source of all heritable variation. In the past few years, whole genome sequencing has allowed direct and comprehensive surveys of mutation patterns in humans and other species. These studies have documented substantial variation in both mutation rates and spectra across primates, the causes of which remain unclear. Here, we review what is currently known about mutation rates in primates, highlight the factors proposed to explain the variation across species, and discuss some implications of these findings on our understanding of the chronology of primate evolution and the process of mutagenesis.

中文翻译：

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灵长类动物突变率的演变。

种系突变是所有可遗传变异的来源。在过去几年中，全基因组测序已经允许对人类和其他物种的突变模式进行直接和全面的调查。这些研究记录了灵长类动物的突变率和光谱的巨大变化，其原因尚不清楚。在这里，我们回顾了目前对灵长类动物突变率的了解，强调了解释物种间变异的因素，并讨论了这些发现对我们理解灵长类动物进化的时间顺序和诱变过程的一些影响。