For decades, scientists have collected genomic information from Indigenous peoples and their ancestors with the goal of elucidating human migration events, understanding ancestral origins, and identifying ancestral variants contributing to disease. However, such studies may not have offered much benefit to the Indigenous groups who contributed DNA, and many have instead perpetuated stereotypes and other harms. With recent advances in genomic technology facilitating the study of both ancient and present-day DNA, researchers and Indigenous communities have new opportunities to begin collaboratively addressing important questions about human health and history. Yet, while there are increased efforts to ethically engage Indigenous communities, more work is still needed as the discipline struggles to absolve itself of the racialized science and extractive biocolonialism that defined its past.

中文翻译：

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基因组的世代：古基因组学技术的进步和美洲原住民的参与。


几十年来，科学家们从土著人民及其祖先那里收集了基因组信息，目的是阐明人类迁徙事件、了解祖先起源并识别导致疾病的祖先变异。然而，此类研究可能并没有给贡献 DNA 的原住民群体带来太多好处，许多研究反而延续了刻板印象和其他危害。随着基因组技术的最新进展促进了古代和现代 DNA 的研究，研究人员和土著社区有了新的机会开始合作解决有关人类健康和历史的重要问题。然而，尽管人们加大了在道德上让土著社区参与的努力，但由于该学科正在努力摆脱定义其过去的种族化科学和榨取式生物殖民主义，因此仍然需要做更多的工作。