Five-Year Survey (2014 to 2018) of Azole Resistance in Environmental Aspergillus fumigatus Isolates from China.,Antimicrobial Agents and Chemotherapy

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Five-Year Survey (2014 to 2018) of Azole Resistance in Environmental Aspergillus fumigatus Isolates from China.
Antimicrobial Agents and Chemotherapy ( IF 4.1 ) Pub Date : 2020-09-21 , DOI: 10.1128/aac.00904-20
Duantao Cao ₁ , Ruilin Wu ₁ , Suxia Dong ₁ , Feiyan Wang ₁ , Chao Ju ₁ , Sumei Yu ₁ , Shiji Xu ₁ , Hua Fang ₁ , Yunlong Yu ₂

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A total of 191 soil samples from Hangzhou, China, were submitted to detect non-wild-type (non-WT) Aspergillus fumigatus and its associated mechanisms. There were 2 (4.7%), 13 (12.4%), and 31 (23.1%) isolates identified as non-WT in 2014, 2016, and 2018, respectively. The resistant mutations of TR34/L98H, TR46/Y121F/T289A, and TR34/L98H/S297T/F495I were found in 3, 5, and 5 non-WT isolates. The G448S mutation, previously only found in clinical settings, was detected in A. fumigatus from soil samples.

更新日期：2020-09-21

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