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Validity of the association between periodontitis and female infertility conditions:a concise review
Reproduction ( IF 3.7 ) Pub Date : 2020-09-01 , DOI: 10.1530/rep-20-0176
Vanessa Machado 1, 2 , Joana Lopes 2 , Mariana Patrão 2 , João Botelho 1, 2 , Luís Proença 3 , José João Mendes 2
Affiliation  

Hormones and inflammatory mechanisms are implicated with female reproductive function, including follicle maturation, ovulation, embryo implantation, and pregnancy. Periodontitis is a chronic inflammatory disease due to a polymicrobial disruption of the homeostasis and may be considered as a potential risk factor that affect female fertility. The role of periodontitis is becoming meaningful, with significant associations with polycystic ovary syndrome, endometriosis and bacterial vaginosis. Further, periodontitis is linked with known risk factors towards female infertility, such as age, obesity, and chronic kidney disease. This review aims to summarize the available evidence on the association between periodontitis and female infertility-associated conditions, and to discuss warranting steps in future research.

中文翻译:

牙周炎与女性不孕症之间关联的有效性:简要回顾

激素和炎症机制与女性生殖功能有关,包括卵泡成熟、排卵、胚胎植入和怀孕。牙周炎是一种慢性炎症性疾病,由多种微生物破坏了体内平衡,可能被认为是影响女性生育能力的潜在危险因素。牙周炎的作用变得有意义,与多囊卵巢综合征、子宫内膜异位症和细菌性阴道病有显着关联。此外,牙周炎与已知的女性不孕风险因素有关,例如年龄、肥胖和慢性肾病。本综述旨在总结关于牙周炎与女性不育相关疾病之间关联的现有证据,并讨论未来研究中的必要步骤。
更新日期:2020-09-01
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