The rapid growth of nanotechnology has increased the occupational exposure to nanomaterials. On the other hand, a growing body of evidence considers exposure to these materials to be hazardous. Therefore, it is necessary to examine the effects of occupational exposure to these materials by different methods. Biological monitoring, especially the investigation of oxidative stress induced by exposure to nanomaterials, can provide useful information for researchers. This study systematically reviews studies that have investigated oxidative stress caused by occupational exposure to nanomaterials. The search was conducted on the PubMed, Scopus and Web of Science databases. Of the 266 studies we obtained in our initial search, eventually 11 were included in our study. There is currently no specific biomarker for investigating oxidative stress induced by exposure to nanomaterials. Therefore, the reviewed studies have used different biomarkers in different biological fluids for this purpose. Also, the methods of assessing occupational exposure to nanomaterials in the investigated studies were very diverse. Given the approach of the investigated studies to biomarkers and exposure assessment methods, finding a specific biomarker for investigating exposure to nanomaterials seems unattainable. But reaching a group of biomarkers, to assess exposure to nanomaterials seems more applicable and achievable.

纳米技术的迅速发展增加了对纳米材料的职业接触。另一方面，越来越多的证据认为暴露于这些物质是有害的。因此，有必要通过不同的方法来检查职业接触这些材料的影响。生物监测，尤其是对暴露于纳米材料引起的氧化应激的研究，可以为研究人员提供有用的信息。这项研究系统地审查了研究，这些研究调查了职业性接触纳米材料引起的氧化应激。搜索在PubMed，Scopus和Web of Science数据库中进行。在我们最初的搜索中获得的266项研究中，最终有11项纳入了我们的研究。目前尚无用于研究由暴露于纳米材料引起的氧化应激的特定生物标记。因此，综述性研究为此目的在不同的生物体液中使用了不同的生物标志物。同样，在所研究的研究中，评估纳米材料职业接触的方法也非常多样。考虑到所研究的生物标志物和暴露评估方法的方法，寻找用于研究纳米材料暴露的特定生物标志物似乎是不可能的。但是接触一组生物标志物以评估纳米材料的暴露似乎更加适用和可实现。在调查的研究中，评估职业接触纳米材料的方法非常多样。鉴于所研究的方法采用生物标志物和暴露评估方法，似乎无法找到用于研究纳米材料暴露的特定生物标志物。但是接触一组生物标志物以评估纳米材料的暴露似乎更加适用和可实现。在所研究的研究中，评估职业接触纳米材料的方法非常多样。鉴于所研究的方法采用生物标志物和暴露评估方法，似乎无法找到用于研究纳米材料暴露的特定生物标志物。但是接触一组生物标志物以评估纳米材料的暴露似乎更加适用和可实现。