Mesenchymal stem cell (MSC) therapy for clinical diseases associated with inflammation and tissue damage has become a progressive treatment strategy. MSCs have unique biological functions, such as homing, immune regulation, and differentiation capabilities, which provide the prerequisites for the treatment of clinical diseases. Oral diseases are often associated with abnormal immune regulation and epithelial tissue damage. In this review, we summarize previous studies that use MSC therapy to treat various oral inflammatory diseases, including oral ulceration, allergic diseases, chemo/radiotherapy-induced oral mucositis, periodontitis, osteonecrosis of the jaw, Sjögren's syndrome (SS), among other similar diseases. We highlight MSC treatment as a promising approach in the management of oral inflammatory diseases, and discuss the obstacles that remain and must be overcome for MSC treatment to thrive in the future.

间充质干细胞 (MSC) 治疗与炎症和组织损伤相关的临床疾病已成为一种渐进式治疗策略。间充质干细胞具有独特的生物学功能，如归巢、免疫调节和分化能力，为临床疾病的治疗提供了先决条件。口腔疾病往往与免疫调节异常和上皮组织损伤有关。在这篇综述中，我们总结了以前使用 MSC 疗法治疗各种口腔炎症疾病的研究，包括口腔溃疡、过敏性疾病、化疗/放疗引起的口腔粘膜炎、牙周炎、颌骨坏死、干燥综合征 (SS) 等类似的疾病。疾病。我们强调 MSC 治疗是治疗口腔炎症疾病的一种有前途的方法，